- Thyroid
- Hypoparathyroidism and Subclinical Hypothyroidism with Secondary Hemochromatosis
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Hyung Ki Jeong, Joon Hwan An, Hyoung Sang Kim, Eun Ae Cho, Min Gui Han, Jung Sik Moon, Hee Kyung Kim, Ho-Cheol Kang
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Endocrinol Metab. 2014;29(1):91-95. Published online March 14, 2014
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DOI: https://doi.org/10.3803/EnM.2014.29.1.91
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Abstract
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Hemochromatosis is an inherited genetic disorder of iron metabolism which can also occur as a secondary result of iron-overload. It leads to organ damage such as cardiomyopathy, liver cirrhosis, hypogonadism, and diabetes. This paper discusses a case of secondary hemochromatosis associated with repeated transfusions, presenting as asymptomatic hypoparathyroidism and subclinical hypothyroidism with multiple organ involvement. The 29-year-old female, who had severe aplastic anemia, received multiple transfusions totaling approximately 1,400 units of red blood cells over 15 years. During her routine laboratory examination, hypocalcemia was detected with decreased intact parathyroid hormone and increased thyroid stimulating hormone. Serum ferritin, iron, and total iron binding capacity had increased to 27,583.03 ng/mL, 291 µg/dL, and 389 µg/dL, respectively. She had unusually bronze skin and computed tomography revealed iron deposition in the thyroid, liver, and heart. Multiorgan involvement as seen in this case is rare in hemochromatosis associated with secondary transfusions. To the best of the author's knowledge, this is the first case report in Korea of hypoparathyroidism and subclinical hypothyroidism due to iron deposition in the parathyroid and thyroid gland.
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Citations
Citations to this article as recorded by
- Hypocalcaemic cardiomyopathy: a description of two cases and a literature review
Martin Válek, Lenka Roblová, Ivan Raška, Dita Schaffelhoferová, Tomáš Paleček ESC Heart Failure.2020; 7(3): 1291. CrossRef - Differential effects of Fe2+ and Fe3+ on osteoblasts and the effects of 1,25(OH)2D3, deferiprone and extracellular calcium on osteoblast viability under iron-overloaded conditions
Kornkamon Lertsuwan, Ketsaraporn Nammultriputtar, Supanan Nanthawuttiphan, Natnicha Tannop, Jarinthorn Teerapornpuntakit, Jirawan Thongbunchoo, Narattaphol Charoenphandhu, Gianpaolo Papaccio PLOS ONE.2020; 15(5): e0234009. CrossRef - Apparent Resolution of Canine Primary Hypoparathyroidism with Immunosuppressive Treatment
J. Warland, B. Skelly, C. Knudsen, M. Herrtage Journal of Veterinary Internal Medicine.2015; 29(1): 400. CrossRef - Articles in 'Endocrinology and Metabolism' in 2014
Won-Young Lee Endocrinology and Metabolism.2015; 30(1): 47. CrossRef
- Thyroid
- Riedel Thyroiditis in a Patient with Graves Disease
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Doo Young Lee, Jung Sik Moon, Ga-Eon Kim, Hee Kyung Kim, Ho-Cheol Kang
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Endocrinol Metab. 2013;28(2):138-143. Published online June 18, 2013
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DOI: https://doi.org/10.3803/EnM.2013.28.2.138
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4,632
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Riedel's thyroiditis is a rare form of infiltrative and inflammatory disease of the thyroid gland and can be associated with systemic fibrotic processes, Hashimoto thyroiditis and Graves disease. Riedel thyroiditis in combination with Graves disease however, is very rare. A 57-year-old woman with a past medical history significant for Graves disease diagnosed 30 years ago presented with an enlarging neck mass and voice changes. Due to suspicion of malignancy, thyroidectomy was performed. Histopathologic examination revealed Riedel thyroiditis. To our knowledge, the association of Riedel thyroiditis with Graves disease has not yet been reported in our country. Here we report a patient with Riedel thyroiditis evolved from antecedent Graves disease.
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Citations
Citations to this article as recorded by
- IgG4-related sclerosing thyroiditis (Riedel-Struma): a review of clinicopathological features and management
Agata Czarnywojtek, Krzysztof Pietrończyk, Lester D. R. Thompson, Asterios Triantafyllou, Ewa Florek, Nadia Sawicka-Gutaj, Marek Ruchała, Maria Teresa Płazinska, Iain J. Nixon, Ashok R. Shaha, Mark Zafereo, Gregory William Randolph, Peter Angelos, Abir Al Virchows Archiv.2023; 483(2): 133. CrossRef - Immunoglobulin G4-Related Thyroid Disease: A Single-Center Experience and Literature Review
Meihua Jin, Bictdeun Kim, Ahreum Jang, Min Ji Jeon, Young Jun Choi, Yu-Mi Lee, Dong Eun Song, Won Gu Kim Endocrinology and Metabolism.2022; 37(2): 312. CrossRef - Riedel Thyroiditis
Aakansha Zala, Thomas Berhane, C Christofer Juhlin, Jan Calissendorff, Henrik Falhammar The Journal of Clinical Endocrinology & Metabolism.2020; 105(9): e3469. CrossRef - Brief Review of Articles in 'Endocrinology and Metabolism' in 2013
Won-Young Lee Endocrinology and Metabolism.2014; 29(3): 251. CrossRef
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